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Parathyroid hormone (PTH) causes


A) increased RANKL and increased OPG.
B) increased RANKL and decreased OPG.
C) decreased RANKL and increased OPG.
D) decreased RANKL and decreased OPG.
E) PTH has no effect on RANKL and OPG.

F) C) and E)
G) B) and D)

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When a fracture begins to heal, one type of bone cell moves into the fracture site and tears down the damaged bone tissue. Which of the following does this?


A) osteoclasts
B) osteoblasts
C) osteons
D) matrix cells
E) osteocytes

F) A) and E)
G) B) and C)

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Spaces in the bone matrix that are occupied by osteocytes are


A) lamellae.
B) lacunae.
C) canaliculi.
D) periosteum.
E) trabeculae.

F) C) and D)
G) A) and B)

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Which of the following statements regarding calcium homeostasis is true?


A) Parathyroid hormone inhibits osteoclast activity.
B) When blood calcium levels are too low, osteoclast activity increases.
C) Increased osteoblast activity increases blood calcium levels.
D) Parathyroid hormone increases calcium loss from the kidney.
E) Calcitonin elevates blood calcium levels.

F) B) and E)
G) B) and D)

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A bone fracture in which one fragment is driven into the cancellous bone of the other fragment is a(an)


A) complicated fracture.
B) impaction fracture.
C) spiral fracture.
D) dentate fracture.
E) greenstick fracture.

F) None of the above
G) C) and E)

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A band of connective tissue that attaches a muscle to a bone is a(n)


A) aponeurosis.
B) ligament.
C) bursa.
D) epimysium.
E) tendon.

F) C) and D)
G) C) and E)

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The proper sequence of events in bone repair is


A) callus formation, hematoma formation, callus ossification, remodeling of bone.
B) remodeling of bone, callus ossification, hematoma formation, callus formation.
C) hematoma formation, callus formation, callus ossification, remodeling of bone.
D) callus ossification, callus formation, remodeling of bone, hematoma formation.
E) hematoma formation, callus ossification, callus formation, remodeling of bone.

F) A) and C)
G) A) and E)

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Which of the following statements about bone growth is TRUE?


A) Most growth in long bones results from interstitial growth.
B) Appositional bone growth results in increased bone length.
C) Endochondral growth in long bones occurs at the epiphyseal plate.
D) In the epiphyseal plate, osteoblasts degenerate to form chondrocytes.
E) Bones can not grow by appositional growth.

F) A) and E)
G) D) and E)

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Bone growth of the epiphysis occurs at the


A) articular cartilage.
B) joint cavity.
C) perichondrium.
D) epiphyseal plate.
E) diaphysis.

F) All of the above
G) B) and E)

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Arrange the following events in endochondral ossification in proper sequence: (1) Cartilage matrix is calcified and chondrocytes die. (2) Chondrocytes hypertrophy. (3) Cartilage model is formed. (4) Osteoblasts deposit bone on the surface of the calcified cartilage called the primary ossification center. (5) Blood vessels from the periosteum invade calcified cartilage bringing in osteoblasts and osteoclasts.


A) 3, 2, 1, 5, 4
B) 3, 2, 5, 4, 1
C) 3, 2, 5, 1, 4
D) 3, 5, 2, 4, 1
E) 1, 3, 4, 5, 2

F) A) and E)
G) C) and D)

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  -This is a diagram of calcium homeostasis. What process is represented by  D ? A)  PTH promotes calcium release into blood by osteoclast. B)  Calcium is removed from blood by osteoblasts. C)  Vitamin D promotes calcium absorption. D)  Calcium is lost in urine. E)  PTH promotes calcium reabsorption from urine. -This is a diagram of calcium homeostasis. What process is represented by "D"?


A) PTH promotes calcium release into blood by osteoclast.
B) Calcium is removed from blood by osteoblasts.
C) Vitamin D promotes calcium absorption.
D) Calcium is lost in urine.
E) PTH promotes calcium reabsorption from urine.

F) A) and E)
G) B) and D)

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What chemical ingested or synthesized by the body is necessary for calcium absorption from the intestines?


A) growth hormone
B) sex hormones
C) parathyroid hormone
D) calcitonin
E) vitamin D

F) All of the above
G) B) and D)

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What are the maintenance cells in bone tissue?


A) osteocytes
B) osteoblasts
C) osteoclasts
D) chondrocytes
E) osteochondral progenitor cells

F) B) and D)
G) B) and E)

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Osteoblasts involved in bone growth in length come primarily from


A) chondrocytes.
B) endothelium of blood vessels.
C) osteocytes.
D) periosteum.
E) connective tissue surrounding blood vessels from the endosteum.

F) A) and B)
G) A) and C)

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You would look for concentric lamellae


A) around the central canal of an osteon.
B) in between osteons.
C) on the outer surface of compact bone tissues.
D) as components of the cartilage.
E) in the bone marrow.

F) C) and D)
G) A) and B)

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An example of a long bone would be


A) the sternum.
B) a rib.
C) a carpal bone.
D) the tibia.
E) the clavicle.

F) B) and E)
G) A) and B)

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Brittle bone disorder is another name for


A) osteoporosis.
B) osteogenesis imperfecta.
C) osteomalacia.
D) scurvy.
E) osteomyelitis.

F) B) and E)
G) B) and D)

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Which type of bone cells give rise to osteoblasts?


A) osteochondral progenitor cell
B) osteoblasts
C) osteocytes
D) osteoclasts

E) C) and D)
F) B) and C)

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Which type of bone has concentric lamellae?


A) spongy bone
B) compact bone
C) both spongy and compact

D) A) and B)
E) A) and C)

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  -This figure illustrates bone growth in length at the Epiphyseal Plate. What is zone  D ? A)  bone of diaphysis B)  zone of calcification C)  zone of hypertrophy D)  zone of proliferation E)  zone of resting cartilage -This figure illustrates bone growth in length at the Epiphyseal Plate. What is zone "D"?


A) bone of diaphysis
B) zone of calcification
C) zone of hypertrophy
D) zone of proliferation
E) zone of resting cartilage

F) A) and E)
G) A) and D)

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